Comparison of application effects of Ciprofol and Propofol anesthesia in painless gastrointestinal endoscopy
Objective:To compare application effects of Ciprofol and Propofol anesthesia in painless gastrointestinal endoscopy.Methods:The clinical data of 60 patients who underwent painless gastrointestinal endoscopy in this hospital from January 2023 to January 2024 were retrospectively analyzed.According to the different anesthetic drugs,they were divided into control group and observation group,30 cases in each group.The observation group was given Propofol combined with Ciprofol anesthesia,while the control group was given Propofol combined with Sufentanil anesthesia.The levels of anesthesia-related indexes(anesthesia induction time,recovery time),diaphragmatic movement indexes[diaphragmatic excursion(DE),diaphragmatic thickening fraction(DTF)]at different times[at the time of entering the room(T0),5 min after anesthesia(T1),and at the end of examination(T2)],the incidence of adverse reactions,and the anesthesia satisfaction were compared between the two groups.Results:There were no significant differences in the anesthesia induction time and the recovery time between the two groups(P>0.05).At T1 and T2,the levels of DE and DTF in the two groups were lower than those at T0,but those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of respiratory depression and injection pain in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,the anesthesia satisfaction of the observation group was 93.33%(28/30),which was higher than 70.00%(21/30)of the control group,and the difference was statistically significant(P<0.05).Conclusions:The Ciprofol anesthesia in the painless gastrointestinal endoscopy can improve the levels of diaphragm movement indexes,reduce the incidence of respiratory depression and injection pain,and improve the anesthesia satisfaction.Moreover,it is superior to Propofol anesthesia.
CiprofolPropofolAnesthesiaPainless gastrointestinal endoscopyRespiratory depressionDiaphragmatic movement