Effects of Feilike mixture combined with conventional Western medicine in treatment of children with acute bronchitis
Objective:To observe effects of Feilike mixture combined with conventional Western medicine in the treatment of children with acute bronchitis.Methods:A prospective study was conducted on 86 children with acute bronchitis admitted to the hospital from June 2021 to December 2022.According to the random number table method,they were divided into control group and observation group,43 cases in each group.The control group was treated with conventional Western medicine,while the observation group was treated with Feilike mixture on the basis of that of the control group.The disappearance time of clinical symptoms(fever,lung rales,cough,wheezing),the levels of inflammatory factors[serum high-sensitivity C-reactive protein(hs-CRP),procalcitonin(PCT),interleukin-8(IL-8),tumor necrosis factor-α(TNF-α)]and blood gas analysis indexes[arterial partial pressure of carbon dioxide(PaCO2),arterial partial pressure of oxygen(PaO2),arterial oxygen saturation(SaO2)]before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The disappearance time of clinical symptoms such as fever,lung rale,cough and wheezing in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).After the treatment,the levels of serum hs-CRP,PCT,IL-8 and TNF-α in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the level of PaCO2 in the observation group was lower than that in the control group,the levels of PaO2 and SaO2 were higher than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Feilike mixture combined with conventional Western medicine in the treatment of the children with acute bronchitis can shorten the disappearance time of clinical symptoms,improve the levels of blood gas analysis indexes,and reduce the levels of inflammatory factors.Moreover,it is superior to simple conventional Western medicine treatment.
Acute bronchitisChildrenFeilike mixtureConventional Western medicineInflammatory factorBlood gas indexAdverse reaction
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维普
