Efficiency of combined detection of serum NT-proBNP,IL-6,PCT and CRP levels in diagnosis of chronic obstructive pulmonary disease complicated with pulmonary infection
Objective:To analyze efficiency of combined detection of N-terminal pro-brain natriuretic peptide(NT-proBNP),interleukin-6(IL-6),procalcitonin(PCT)and C-reactive protein(CRP)levels in diagnosis of chronic obstructive pulmonary disease(COPD)complicated with pulmonary infection.Methods:The clinical data of 84 patients with COPD complicated with pulmonary infection admitted to this hospital from May 2021 to May 2023 were retrospectively analyzed and they were set as the infection group.In addition,79 patients with COPD without pulmonary infection during the same period were set as the non-infection group.The levels of serum NT-proBNP,IL-6,PCT and CRP were compared between the two groups.The receiver operating curve(ROC)was used to analyze the efficiencies of NT-proBNP,IL-6,PCT and CRP single and combined detection in the diagnosis of COPD complicated with pulmonary infection.Results:The levels of NT-proBNP,IL-6,PCT and CRP in the infection group were higher than those in the non-infection group,and the differences were statistically significant(P<0.05).The ROC curve showed that the area under the curve of single and combined detection of NT-proBNP,IL-6,PCT and CRP levels in the diagnosis of COPD complicated with pulmonary infection were 0.808,0.796,0.825,0.816 and 0.913,separately,and the combined detection had the highest diagnostic efficiency.Conclusions:The efficiency of combined detection of serum NT-proBNP,IL-6,PCT and CRP levels in the diagnosis of COPD complicated with pulmonary infection is higher than that of single detection of the four.
万方数据
维普
