摘要
目的:分析晋江市371例发生性早熟患儿的影响因素.方法:选取2021年9月至2023年9月晋江市371例性早熟患儿进行横断面研究,设为观察组,另选取晋江市同期371名体检健康儿童作为对照组,收集所有受试者的一般资料,并采用Logistic回归分析性早熟发生的影响因素.结果:观察组母亲妊娠期间保胎、母亲初潮年龄≤13岁、有性早熟家族史、出生时窒息、服用营养滋补品每周≥3次、高蛋白饮食每周≥3次等占比均高于对照组,差异有统计学意义(P<0.05);两组年龄、性别、独生子女、居住区域、父母文化程度、课业负担、抚养方式、父母人均年收入、每日睡眠时间、早产儿、亮灯睡觉等占比比较,差异均无统计学意义(P>0.05);Logistic回归分析结果显示,母亲妊娠期间保胎、母亲初潮年龄≤13岁、有性早熟家族史、出生时窒息、服用营养滋补品每周≥3次、高蛋白饮食每周≥3次均属于影响晋江地区371例儿童发生性早熟的危险因素(OR>1,P<0.05).结论:母亲妊娠期间保胎、母亲初潮年龄≤13岁、有性早熟家族史、出生时窒息、服用营养滋补品每周≥3次、高蛋白饮食每周≥3次均属于影响晋江地区371例儿童发生性早熟的危险因素.
Abstract
Objective:To analyze influencing factors of 371 children with sexual precocity in Jinjiang city. Methods:A cross-sectional study was conducted on 371 children with sexual precocity from September 2021 to September 2023. They were set as the observation group. Another 371 healthy children who underwent physical examination in Jinjiang city during the same period were selected as the control group. The general data of all subjects were collected. Logistic regression was used to analyze the influencing factors of sexual precocity. Results:The proportions of maternal tocolysis during pregnancy,maternal menarche age ≤ 13 years old,family history of sexual precocity,birth asphyxia,taking nutritional supplements≥3 times a week,and high protein diet ≥ 3 times a week in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05).There were no significant differences in the proportions of age,gender,only child,living area,parental education level,school burden,parenting style,parental annual income per capita,daily sleep time,premature infants and light sleep between the two groups (P>0.05). Logistic regression analysis showed that maternal tocolysis during pregnancy,maternal menarche age≤13 years old,family history of sexual precocity,birth asphyxia,taking nutritional supplements≥3 times a week,and high protein diet≥3 times a week were all risk factors affecting the occurrence of sexual precocity in the 371 children in Jinjiang area (OR>1,P<0.05). Conclusions:Maternal tocolysis during pregnancy,maternal menarche age≤13 years old,family history of sexual precocity,birth asphyxia,taking nutritional supplements≥3 times a week,and high protein diet≥3 times a week are the risk factors affecting the 371 children with sexual precocity in Jinjiang area.
维普
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