中国民康医学2024,Vol.36Issue(23) :125-127.DOI:10.3969/j.issn.1672-0369.2024.23.039

血清卵泡刺激素、黄体生成素、泌乳素水平与多囊卵巢综合征患者胰岛素抵抗的相关性

Correlations between serum follicle stimulating hormone,luteinizing hormone,prolactin levels and insulin resistance in patients with polycystic ovary syndrome

马丽平 吕伟霞
中国民康医学2024,Vol.36Issue(23) :125-127.DOI:10.3969/j.issn.1672-0369.2024.23.039

血清卵泡刺激素、黄体生成素、泌乳素水平与多囊卵巢综合征患者胰岛素抵抗的相关性

Correlations between serum follicle stimulating hormone,luteinizing hormone,prolactin levels and insulin resistance in patients with polycystic ovary syndrome

马丽平 1吕伟霞2
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作者信息

  • 1. 镇平县石佛寺镇卫生院妇产科,河南 南阳 474284
  • 2. 镇平县人民医院妇产科,河南 南阳 474284
  • 折叠

摘要

目的:分析血清卵泡刺激素(FSH)、黄体生成素(LH)、泌乳素(PRL)水平与多囊卵巢综合征(PCOS)患者胰岛素抵抗的相关性.方法:回顾性分析2020—2022年该院收治的80例PCOS患者的临床资料,设为观察组,另选取同期80名健康体检者,设为对照组.比较两组FSH、LH、PRL水平及胰岛素抵抗指数(HOMA-IR),采用Pearson相关性分析血清FSH、LH、PRL水平与HOMA-IR的相关性.结果:两组FSH水平比较,差异无统计学意义(P>0.05);观察组LH水平高于对照组,PRL水平低于对照组,差异均有统计学意义(P<0.05);观察组HOMA-IR高于对照组,差异有统计学意义(P<0.05);经Pearson相关性分析结果显示,LH水平与HOMA-IR呈正相关(r>0,P<0.05),PRL水平与HOMA-IR呈负相关(r<0,P<0.05).结论:血清LH水平与PCOS患者HOMA-IR呈正相关,PRL水平与PCOS患者HOMA-IR呈负相关.

Abstract

Objective:To analyze correlations between serum follicle stimulating hormone (FSH),luteinizing hormone (LH),prolactin (PRL) levels and insulin resistance in patients with polycystic ovary syndrome (PCOS). Methods:The clinical data of 80 PCOS patients admitted to this hospital from 2020 to 2022 were retrospectively analyzed and they were set as the observation group;another 80 healthy subjects were selected as the control group. The levels of FSH,LH,PRL and homeostasis model assessment of insulin resistance (HOMA-IR) were compared between the two groups. Pearson correlation analysis was used to analyze the correlations between the serum FSH,LH,PRL levels and HOMA-IR. Results:There was no significant difference in the FSH level between the two groups (P>0.05). The LH level of the observation group was higher than that of the control group,the PRL level was lower than that of the control group,and the differences were statistically significant (P<0.05). The level of HOMA-IR in the observation group was higher than that in the control group,and the difference was statistically significant (P<0.05). Pearson correlation analysis showed that the LH level was positively correlated with HOMA-IR (r>0,P<0.05),and the PRL level was negatively correlated with HOMA-IR (r<0,P<0.05). Conclusions:The serum LH level is positively correlated with HOMA-IR in POCS patients,while the PRL level is negatively correlated with HOMA-IR in POCS patients.

关键词

多囊卵巢综合征/卵泡刺激素/黄体生成素/泌乳素/胰岛素抵抗

Key words

Polycystic ovary syndrome/Follicle stimulating hormone/Luteinizing hormone/Prolactin/Insulin resistance

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出版年

2024
中国民康医学
中国社会工作协会

中国民康医学

影响因子:0.649
ISSN:1672-0369
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