Application effects of anesthesia induction of Esketamine combined with Propofol in painless gastrointestinal endoscopy
Objective:To observe application effects of anesthesia induction of Esketamine combined with Propofol in painless gastrointestinal endoscopy. Methods:The clinical data of 94 patients who underwent painless gastrointestinal endoscopy in this hospital from January December 2023 were retrospectively analyzed. According to different anesthesia induction methods,they were divided into observation group and control group,47 cases in each group. The control group was induced by Propofol anesthesia,while the observation group was induced by Esketamine combined with Propofol anesthesia. The anesthesia onset time,the recovery room stay time,the post-anesthesia discharge score scale (PADSS) score at the time of discharge from the hospital,the vital sign indicators[mean arterial pressure (MAP),heart rate,blood oxygen saturation (SpO2)]levels at different times[before anesthesia induction (T0),immediately after anesthesia induction (T1),mirror into the end of the ileum (T2),immediately after awakening (T3)]and the incidence of adverse reactions were compared between the two groups. Results:The anesthesia onset time in the observation group was shorter than that in the control group,and the difference was statistically significant (P<0.05). At T1 and T2,the MAP and heart rate levels of the two groups were lower than those at T0,but those in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05). The incidence of adverse reactions in the observation group was 8.51%,which was significantly lower than 23.40% in the control group,and the difference was statistically significant (P<0.05). There were no significant differences in the recovery room stay time,the PADSS score at discharge and the SpO2 level at different time (T0,T1,T2,T3) between the two groups (P>0.05). Conclusions:The anesthesia induction of Esketamine combined with Propofol in painless gastrointestinal endoscopy can shorten the anesthesia onset time,improve the levels of MAP and heart rate,and reduce the incidence of adverse reactions. Moreover,it is superior to simple Propofol anesthesia induction.