Correlations among serum D-dimer,platelet count,C-reactive protein levels and severity of ulcerative colitis
Objective:To analyze correlations among serum D-dimer (D-D),platelet count (PLT),C-reactive protein (CRP) levels and severity of ulcerative colitis. Methods:The clinical data of 100 patients with ulcerative colitis admitted to Luoyang third people's hospital from 2020 to 2022 were retrospectively analyzed,and they were set as the study group. At the same time,100 healthy subjects were set as the control group. The levels of serum D-D,PLT and CRP were compared between the two groups. The severity of the patients' conditions was assessed according to the modified Mayo score. The levels of serum D-D,PLT and CRP among the patients with ulcerative colitis in remission stage,active stage and different active stages were compared,and their correlations with the severity of ulcerative colitis were analyzed. Results:The levels of serum D-D,PLT and CRP in the study group were higher than those in the control group,and the differences were statistically significant (P<0.05). The levels of serum D-D,PLT and CRP in the patients in active stage were higher than those in the patients with remission stage,and the differences were statistically significant (P<0.05). The levels of serum D-D,PLT and CRP in the patients with severe and moderate activity were higher than those in the patients with mild activity,those in the patients with severe activity were higher than those in the patients with moderate activity,and the differences were statistically significant (P<0.05). Pearson correlation analysis showed that the serum D-D,PLT and CRP levels were positively correlated with the severity of ulcerative colitis (r>0,P<0.05). Conclusions:The serum D-D,PLT and CRP levels are positively correlated with the severity of ulcerative colitis.
万方数据
维普
