Comparison of effects of percutaneous minimally invasive plate osteosynthesis and locking compression plate internal fixation in treatment of patients with limb fractures
Objective:To compare effects of percutaneous minimally invasive plate osteosynthesis and locking compression plate internal fixation in treatment of patients with limb fractures. Methods:A prospective study was conducted on 60 patients with limb fractures admitted to the hospital from July 2021 to December 2022. According to the random number table method,they were divided into control group and observation group,30 cases in each group. The control group was treated with locking compression plate internal fixation,while the observation group was treated with percutaneous minimally invasive plate osteosynthesis. The levels of surgery-related indexes (hospitalization time,intraoperative blood loss,fracture healing time),the serum biochemical indexes[serum receptor activator of nuclear factor-κB ligand (RANKL),type I collagen carboxy terminal peptide β special sequence (β-CTX),basic fibroblast growth factor (bFGF),bone morphogenetic protein-2 (BMP-2)]levels,the limb motor function[Fugl-Meyer motor assessment (FMA)]before and after surgery,and the incidence of postoperative complications were compared between the two groups. Results:The hospitalization time and the fracture healing time of the observation group were shorter than those of the control group,the intraoperative blood loss was less than that of the control group,and the differences were statistically significant (P<0.05). Four weeks after surgery,the levels of β-CTX and RANKL in the two groups were lower than those before surgery,and those in the observation group were lower than those in the control group;the levels of bFGF and BMP-2 in the two groups were higher than those before surgery,and those in the observation group were higher than those in the control group;and the differences were statistically significant (P<0.05). Four weeks after surgery,the scores of upper limb function and lower limb function in the two groups were higher than those before surgery,those in the observation group were higher than those in the control group,and the differences were statistically significant (P<0.05). However,there was no significant difference in the incidence of complications between the two groups (P>0.05). Conclusions:Percutaneous minimally invasive plate osteosynthesis in the treatment of the patients with limb fractures can significantly reduce the hospitalization time,reduce the intraoperative blood loss,improve the fracture healing and the repair ability,which is beneficial to the functional rehabilitation of these patients,the effect is better than that of locking compression plate internal fixation.
Limb fracturePercutaneous minimally invasive plate osteosynthesisLocking compression plate fixationLimb motor function
万方数据
维普
