中国民族医药杂志2024,Vol.30Issue(11) :13-14.

藏药七十味珍珠丸对大鼠脑损伤后星形胶质细胞的影响

The effect of Ratnasampil on astrocytes after brain injury in rats

马辉 廉会娟
中国民族医药杂志2024,Vol.30Issue(11) :13-14.

藏药七十味珍珠丸对大鼠脑损伤后星形胶质细胞的影响

The effect of Ratnasampil on astrocytes after brain injury in rats

马辉 1廉会娟1
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作者信息

  • 1. 西藏民族大学医学院,咸阳 陕西 712082
  • 折叠

摘要

目的:通过大鼠脑损伤模型,验证藏药七十味珍珠丸对大鼠脑损伤区星形胶质细胞的影响.方法:SD大鼠随机分为正常对照组、创伤模型组、药物治疗组,造模后灌胃给药3d后,对损伤区域进行星形胶质细胞免疫荧光染色及细胞计数.结果:药物治疗组损伤区星形胶质细胞数量明显降低,具有统计学意义(P<0.05).结论:七十味珍珠丸可降低大鼠脑损伤后损伤区的星形胶质细胞数量,发挥神经保护作用.

Abstract

Objective:To verify the effect of Tibetan medicine Ratnasampil on astrocytes in the brain injury area of rats through a rat brain injury model.Method:SD rats were randomly divided into a normal control group,a trauma model group,and a drug treatment group.After modeling and gavage administration for 3 days,astrocyte immunofluorescence staining and cell counting were performed on the damaged area.Result:The number of astrocytes in the injury area of the drug treatment group was significantly reduced,with statistical significance(P<0.05).Conclusion:Ratnasampil can reduce the number of astrocytes in the damaged area of rats after brain injury and exert neuroprotective effects.

关键词

星形胶质细胞/七十味珍珠丸/脑损伤

Key words

astrocyte/Ratnasampil/brain injury

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出版年

2024
中国民族医药杂志
全国中医药图书情报工委会,内蒙古中蒙医研究所

中国民族医药杂志

影响因子:0.28
ISSN:1006-6810
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