Infection genotype and distribution characteristics of human papillomavirus in 889 male patients
Objective To investigate the infection and distribution characteristics of human papillomavirus(HPV)in local male patients.Methods Quantitative PCR was used to detect 23 types of HPV and to analyze the results of the scraping on the surface of the external genitalia.Results Among the 889 male specimens,238 samples were positive(26.77%).The subtypes with the highest infection rates were HPV 6(6.64%),16(4.05%),11(3.26%),58(3.03%),and 52(2.47%).HPV infection was mainly single infection,and multiple infection was mainly mixed infection.There were significant differences in the positive rate of high and low risk between different infection types(P<0.05).Among the population presented,the 21-30 and 31-40 age groups had the highest number of visits and infections.After grouping by age,the positive detection rate was highest in the age group under 20 years old(43.75%),followed by 50 years old(34.09%),and there were significant differences between the positive detection rate and high-low risk positive detection rate between different age groups(P<0.05).Compared with the subtypes and distribution characteristics of HPV infection in urology and dermatology patients,there was no significant difference between the two groups.Conclusions The positive rate of HPV in male patients was 26.77%,and the most common types were HPV6,16,11,58,and 52.The infection status of different ages is different,and attention should be paid to the screening and prevention of HPV in male external genitalia.