首页|889例男性患者人乳头瘤病毒的感染分型及分布特点

889例男性患者人乳头瘤病毒的感染分型及分布特点

扫码查看
目的 了解当地男性患者人乳头瘤病毒(HPV)的感染情况.方法 采用荧光定量PCR(Polymerase Chain Reaction)法对男性患者外生殖器表面刮擦物进行HPV 23种分型检测及结果分析.结果 889例男性标本中,238例检测为阳性(26.77%).感染率最高的亚型依次是 HPV6(6.64%)、16(4.05%)、11(3.26%)、58(3.03%)和 52(2.47%).HPV感染以单一感染为主,多重感染以高低混合型感染为主,高-低危组间阳性率具有显著差异(P<0.05).就诊人群中,21~30岁和31~40岁年龄段的就诊人数和感染人数最多;按年龄分组后,阳性检出率在20岁以下年龄组最高(43.75%),50岁以上次之(34.09%),不同年龄组间阳性检出率和高-低危阳性检出率均具有显著差异(P<0.05).对比泌尿外科和皮肤科患者HPV感染的分型与分布特点,两科室间均无明显差异.结论 门诊男性患者HPV阳性率为26.77%,以HPV6、16、11、58、52亚型为主,不同年龄阶段的感染情况不同,需重视男性外生殖器HPV的筛查和预防.
Infection genotype and distribution characteristics of human papillomavirus in 889 male patients
Objective To investigate the infection and distribution characteristics of human papillomavirus(HPV)in local male patients.Methods Quantitative PCR was used to detect 23 types of HPV and to analyze the results of the scraping on the surface of the external genitalia.Results Among the 889 male specimens,238 samples were positive(26.77%).The subtypes with the highest infection rates were HPV 6(6.64%),16(4.05%),11(3.26%),58(3.03%),and 52(2.47%).HPV infection was mainly single infection,and multiple infection was mainly mixed infection.There were significant differences in the positive rate of high and low risk between different infection types(P<0.05).Among the population presented,the 21-30 and 31-40 age groups had the highest number of visits and infections.After grouping by age,the positive detection rate was highest in the age group under 20 years old(43.75%),followed by 50 years old(34.09%),and there were significant differences between the positive detection rate and high-low risk positive detection rate between different age groups(P<0.05).Compared with the subtypes and distribution characteristics of HPV infection in urology and dermatology patients,there was no significant difference between the two groups.Conclusions The positive rate of HPV in male patients was 26.77%,and the most common types were HPV6,16,11,58,and 52.The infection status of different ages is different,and attention should be paid to the screening and prevention of HPV in male external genitalia.

malehuman papillomavirussubtypes

沈萍、倪艳颖、姜忠彩

展开 >

航空总医院病理科(北京 100012)

男性 人乳头瘤病毒 分型

2024

中国男科学杂志
上海交通大学医学院,国家人口和计划生育委员会科学技术研究所

中国男科学杂志

CSTPCD
影响因子:0.437
ISSN:1008-0848
年,卷(期):2024.38(3)