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Characterization of MicroRNA* Species in Peking Duck Skin

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
  • 维普
A substantial fraction of miRNA*species are conserved in animals and can repress activities of target genes. This study aims to investigate the miRNA*species in duck skin by using Solexa sequencing. We obtained a total of 96 miRNA*species in two skin small RNA libraries and identified 56 miRNA/miRNA*(miR/miR*) pairs. Nucleotide bias of miRNA*indicated that the priority was C>A>U>G for the first nucleotide and U>C>A>G for the last nucleotide. Comparison analyses showed that 3′-U accounted for a higher proportion in the 56 miR/miR*pairs. Among the top 20 expressed miRNA*species, 17 were shared by two libraries and most of the miRNA*species were highly conservative, especially in the“seed region”. miR-199a*were expressed highly in our samples, which was also previously shown abundant in mouse hair follicle. Furthermore, four miRNA*species were predicted to target their genes in signal pathways of feather follicle development and feather morphogenesis despite very low levels.

Peking duckmiRNA star species (miRNA*)skinnucleotide bias

ZHANG Li、XIE Xiu-juan、JIA Shan-gang、XIAO Mei、LIN Shu-dai、AN Li-long、LUO Wen、JIA Xin-zheng、NIE Qing-hua、ZHANG Xi-quan

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Agricultural College, Guangdong 0cean University, Zhanjiang 524088, P.R.China

Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, South China Agricultural University, Guangzhou 510642, P.R.China

Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, P.R.China

2013

农业科学学报(英文)
中国农业科学院农业信息研究所

农业科学学报(英文)

CSCDSCI
影响因子：0.576
ISSN：2095-3119
年,卷(期)：2013.(9)
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