首页|Adipokinetic hormone signaling regulates adult dehydration resistance in the migratory locust

Adipokinetic hormone signaling regulates adult dehydration resistance in the migratory locust

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
Drought events have become more severe under climate change,and this can pose a major threat to the survival of various organisms.The molecular mechanisms involved in dehydration resistance are not well known.Here,adults of the migratory locust,Locusta migratoria,were subjected to food-mediated dehydration,and adipokinetic hormone(AKH)signaling was found to play a key role in regulating dehydration resistance.Specifically,dehydration shortened the lifespan,increased the body weight loss,and reduced the water loss rate in adult locusts.Global transcriptome profiles revealed variations in tissue-specific gene expression between dehydration-resistant locusts and normal locusts.Importantly,dehydration selection and exposure induced prominent expression of AKH genes in the retrocerebral complex of adult locusts.Furthermore,individual knockdown of AKH1,AKH2,or AKH receptor(AKHR)accelerated water loss and shortened the lifespan of adult locusts under dehydration conditions,and trehalose supplementation ameliorated the negative effects caused by interference with AKH or AKHR.These findings demonstrated that AKH/AKHR signaling-dependent trehalose metabolism plays a crucial role in regulating locust dehydration resistance and thus provide novel insights into the regulatory mechanism underlying drought resistance.

adipokinetic hormoneadipokinetic hormone receptortrehalosedehydration resistanceLocusta migratoria

Xianliang Huang、Dai Shi、Kai Deng、Shuzhen Jia、Ding Ding、Li Hou、Bing Chen

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College of Life Sciences,Hebei University,Baoding 071002,China

Hebei Basic Science Center for Biotic Interaction,Hebei University,Baoding 071002,China

State Key Laboratory of Integrated Management of Pest Insects and Rodents,Institute of Zoology,Chinese Academy of Sciences,Beijing 100101,China

National Key Research and Development Program of ChinaNational Natural Science Foundation of ChinaHebei Natural Science Foundation,ChinaHebei Natural Science Foundation,ChinaHebei Natural Science Foundation,China

2022YFD140050332102208C2022201042C2021201052C2023201075

2024

10.1016/j.jia.2024.03.019

农业科学学报(英文)
中国农业科学院农业信息研究所

农业科学学报(英文)

CSTPCD
影响因子：0.576
ISSN：2095-3119
年,卷(期)：2024.23(9)