Research progress on transformation and application of chemical components of traditional Chinese medicine by fungal fermentation
Fungal fermentation can cause a variety of chemical reactions such as glycosylation,hydroxylation and methylation of the chemical compo-nents of traditional Chinese medicine,and produce abundant secondary metabolites.Fungal fermentation has the advantages of high efficiency,mild conditions,strong selectivity,no pollution to the environment,and multiple reaction types,but the stability and controllability of the fermentation pro-cess have always been a problem.In this paper,the fermentation technology of traditional Chinese medicine and fungi commonly used in the fermen-tation were summarized,the transformation mechanism of traditional Chinese medicine chemical components(flavonoids,alkaloids,steroids,ter-penoids,quinones,phenylpropanoids)was reviewed,and the application of common fungi in the transformation of traditional Chinese medicine com-ponents was summarized,so as to provide references for the subsequent research and development of traditional Chinese medicine components with the rational use of fungi.
fungifermentationchemical components of traditional Chinese medicinetransformation mechanismapplication
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