首页|止脱茁发方治疗湿热型头皮脂溢性皮炎30例临床观察

止脱茁发方治疗湿热型头皮脂溢性皮炎30例临床观察

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目的 观察止脱茁发方治疗湿热型头皮脂溢性皮炎的疗效.方法 将60例头皮脂溢性皮炎患者随机分为两组,试验组30例,使用止脱茁发方治疗,对照组30例,使用2%酮康唑洗剂治疗,1次/周,治疗4周.治疗结束后随访4周,治疗前后记录临床症状评分、起效时间、马拉色菌镜检结果、不良反应及复发情况.8周后进行疗效判定.结果 治疗组临床症状指标总疗效有效率为86.20%(25/29),对照组临床症状指标总疗效有效率为60.71%(17/28),治疗组疗效高于对照组(P<0.05).两组在瘙痒、头皮屑、头皮出油、头皮红斑/炎性丘疹等临床症状均明显改善(P<0.05),试验组在脱发症状改善方面差异有统计学意义(P<0.05),对照组脱发改善不明显(P>0.05).治疗组改善瘙痒、头皮屑、头皮出油、脱发等的平均起效时间短于对照组(P<0.05);两组改善头皮红斑/炎性丘疹的平均起效时间差异无统计学意义(P>0.05).两组在马拉色菌有效清除率方面差异无统计学意义(P>0.05).两组均未出现明显不良反应.随访完成后,试验组复发率低于对照组(P<0.05).结论 止脱茁发方治疗湿热型头皮脂溢性皮炎起效快,无明显不良反应,与酮康唑洗剂相比具有一定优势.
Clinical Observation of"Zhituo Zhuofa Formula"on Scalp Seborrheic Dermatitis of Damp-Heat Type
Objective To observe the effectiveness of Zhituo Zhuofa Formula in ftreating scalp seborrheic dermatitis.Methods Sixty patients with SSD were randomly divided into two groups,the test group(n=30)was treated with Zhituo Zhufa Formula,while the control group(n=30)was treated with 2%ketoconazole,both groups received treatment once a week for a total of 4 weeks.Follow up for 4 weeks,calculate the clinical symptom scores,Malassezia microscopy results,adverse reactions,and recurrence.Results The effective rate of the treatment group was 86.20%(25/29),while the effective rate of the control group was 60.71%(17/28).The therapeutic effect of the treatment group was higher than that of the control group(P<0.05).After treatment,both groups showed significant improvement in clinical symptoms such as itching,dandruff,scalp oiliness,and scalp erythema/inflammatory papules(P<0.05).However,the experimental group was able to control hair loss symptoms(P<0.05),while the control group had no such effect(P>0.05).The comparison between the two groups showed that the treatment group had a better average onset time in improving itching,dandruff,scalp oiliness,hair loss,etc.than the control group(P<0.05).There was no statistically significant difference(P>0.05)in the effective clearance rate of Malassezia between the two groups.Both groups did not show any significant adverse reactions.After follow-up,the recurrence rate in the experimental group was lower than that in the control group(P<0.05).Conclusion Zhituo Zhuofa Formula has a fast onset and no significant adverse reactions in treating scalp seborrheic dermatitis of damp heat type,and has certain advantages compared to Caile Lotion.

Scalp seborrheic dermatitis,damp heat typeZhituo Zhuofa FormulaImprovement of symptoms

唐磊、傅强、黄富均、黄梦雅、刘林、刘娅、周汛

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重庆市中医院皮肤美容科,重庆 400021

头皮脂溢性皮炎,湿热型 止脱茁发方 症状改善

2025

中国皮肤性病学杂志
西安交通大学

中国皮肤性病学杂志

北大核心
影响因子:0.66
ISSN:1001-7089
年,卷(期):2025.39(1)