Clinical Observation of"Zhituo Zhuofa Formula"on Scalp Seborrheic Dermatitis of Damp-Heat Type
Objective To observe the effectiveness of Zhituo Zhuofa Formula in ftreating scalp seborrheic dermatitis.Methods Sixty patients with SSD were randomly divided into two groups,the test group(n=30)was treated with Zhituo Zhufa Formula,while the control group(n=30)was treated with 2%ketoconazole,both groups received treatment once a week for a total of 4 weeks.Follow up for 4 weeks,calculate the clinical symptom scores,Malassezia microscopy results,adverse reactions,and recurrence.Results The effective rate of the treatment group was 86.20%(25/29),while the effective rate of the control group was 60.71%(17/28).The therapeutic effect of the treatment group was higher than that of the control group(P<0.05).After treatment,both groups showed significant improvement in clinical symptoms such as itching,dandruff,scalp oiliness,and scalp erythema/inflammatory papules(P<0.05).However,the experimental group was able to control hair loss symptoms(P<0.05),while the control group had no such effect(P>0.05).The comparison between the two groups showed that the treatment group had a better average onset time in improving itching,dandruff,scalp oiliness,hair loss,etc.than the control group(P<0.05).There was no statistically significant difference(P>0.05)in the effective clearance rate of Malassezia between the two groups.Both groups did not show any significant adverse reactions.After follow-up,the recurrence rate in the experimental group was lower than that in the control group(P<0.05).Conclusion Zhituo Zhuofa Formula has a fast onset and no significant adverse reactions in treating scalp seborrheic dermatitis of damp heat type,and has certain advantages compared to Caile Lotion.
Scalp seborrheic dermatitis,damp heat typeZhituo Zhuofa FormulaImprovement of symptoms