首页|难辨认癣591例临床表现、病原学及皮肤镜特征分析

难辨认癣591例临床表现、病原学及皮肤镜特征分析

Clinical Manifestations,Etiology and Dermoscopic Features of 591 Patients with Tinea Incognito

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目的 分析难辨认癣患者临床表现、病原学及皮肤镜征象,提高对难辨认癣的认识,为临床诊断提供参考.方法 回顾2013年1月—2023年12月武汉市第一医院皮肤科经真菌学检查确诊的591例难辨认癣患者临床资料、致病菌谱、直接镜检特征,并对其中241例资料完整患者的发病部位与临床表现及101例行影像学检查患者的皮肤镜征象进行分析.结果 591例难辨认癣患者中,男254例,女337例,年龄5 d~85岁,平均(36.60±22.89)岁,面颈部是最常受累的部位(51.04%),湿疹型是最常见的临床表现(48.96%).红色毛癣菌是主要致病菌(58.71%),儿童以亲动物性皮肤癣菌感染为主(80.38%),成人以亲人性皮肤癣菌感染为主(80.37%).真菌直接镜检示亲人性皮肤癣菌以粗大分隔的菌丝多见,亲动物性皮肤癣菌除菌丝外,常伴毳毛内或毳毛外孢子及菌丝.皮肤镜下最常见的征象为脱屑(60.40%),就年龄而言,成人脱屑患者比例明显高于儿童,儿童患者毛囊微脓疱比例明显高于成人,差异有统计学意义(P<0.05);就致病菌来源而言,亲人性皮肤癣菌感染主要表现为树枝状血管且以螺旋状毳毛多见,亲动物性皮肤癣菌感染以点状或球状血管为主,毳毛多表现为锯齿状毳毛,差异有统计学意义(P<0.05).结论 难辨认癣临床表现多样,易误诊,真菌镜检结合皮肤镜检查有助于判断难辨认癣致病菌来源,减少漏诊误诊.
Objective To analyze the clinical manifestations,etiology and dermoscopic features of patients with tinea incognito,to improve the understanding of tinea incognito,and to provide reference for clinical diagnosis.Methods The clinical data,pathogenic bacterial spectrum,direct microscopic and dermoscopic features of 591 patients with tinea incognito diagnosed by mycological examination in the Outpatient Department of Wuhan No.1 Hospital from January 2013 to December 2023 were reviewed.In addition,the pathogenic site and clinical manifestations of 241 patients with complete data and the dermoscopic signs of 101 patients undergoing imaging examination were analyzed.Results Among 591 patients with tinea incognito,254 were males and 337 were females,aged 5 days to 85 years.Faciocervical region was the most commonly involved(51.04%),and eczema-like skin was the most common clinical manifestation(48.96%).Trichophyton rubrum was the main pathogen of tinea incognito(58.71%).The infection of children was mainly zoophilic(80.38%),and the infection of adult was mainly anthrophilic(80.37%).Direct microscopic examination of fungi showed that anthrophilic was mainly composed of coarse separated hyphae.In addition to hyphae,zoophilic was often associated with endothix or ectothrix infection in vellus hair.The most common dermatoscopic sign was scale(60.40%).In terms of age,the proportion of patients with scales in adults was significantly higher than that in children,and the proportion of follicular pustules in children was significantly higher than that in adults,suggesting significant differences(P<0.05).In terms of the isolated fungal species,tinea incognito caused by anthrophilic infection was mainly manifested in arborizing vessels and corkscrew vellus hairs,whereas zoophilic infection was mainly manifested in dotted or glomerular vessels and zigzag vellus hairs,showing significant differences(P<0.05).Conclusion The clinical manifestations of tinea incognito are varied and prone to misdiagnosis.Fungal microscopy and dermoscopy can help to identify the source of pathogens and reduce missed diagnosis and misdiagnosis.

Tinea incognitoDermatophytesClinical characteristicsDermoscopic signs

喻惠元、陈尊义、陈瑶、董碧麟、曾志良、童中胜

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武汉市第一医院皮肤科,湖北武汉 430022

难辨认癣 皮肤癣菌 临床特征 皮肤镜征象

2025

中国皮肤性病学杂志
西安交通大学

中国皮肤性病学杂志

北大核心
影响因子:0.66
ISSN:1001-7089
年,卷(期):2025.39(1)