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玫瑰痤疮患者435例生活习惯与发病影响因素分析

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目的 探究玫瑰痤疮患者的生活习惯与疾病发病之间的关系,期望识别影响玫瑰痤疮发病的关键因素,为预防和控制疾病提供实践指导.方法 本研究采用问卷调查和临床访谈相结合的方法,运用皮肤病生活质量指数(DLQI)、Skindex-16评分、欧洲五维度五水平(EQ-5D-5L)问卷、焦虑自评量表(SAS)、抑郁自评量表(SDS)及匹兹堡睡眠质量指数(PSQI)多维度评分体系对435例玫瑰痤疮患者的基本信息、临床特征、生活质量和加重因素进行评估.通过运用统计学方法对收集到的数据进行深入分析,揭示生活习惯与玫瑰痤疮发病之间的潜在联系.结果 435例患者中以女性为主,平均年龄为(40.97±11.34)岁,病程为(2.94±0.87)年.其中红斑毛细血管扩张型(ETR)和丘疹脓疱型(PPR)为玫瑰痤疮的主要类型,皮损好发于面颊(72.18%)和鼻部(64.37%).多数患者的红斑和整体病情严重程度均为中度(66.06%和86.67%).生活质量测评DLQI、Skindex-16以及SAS、SDS等量表显示患者的生活质量与健康状况受到显著影响.EQ-5D-5L和VAS评分表明,患者整体健康水平接近中等,但焦虑或抑郁症状普遍(49.86%).部分患者睡眠质量良好,但仍有少数患者存在严重睡眠障碍.进一步分析揭示,季节性因素(如温差、阳光、高温)、生活习惯(如锻炼过量、情绪压力、饮酒)、月经周期、化妆品使用和辛辣食物摄入与玫瑰痤疮严重程度显著相关(P<0.05).多因素Logistic回归分析确认这些因素(OR>1,P<0.05)均为玫瑰痤疮严重程度的危险因素.结论 玫瑰痤疮患者存在一定程度的健康相关生活质量下降、心理困扰及睡眠质量差异,且温差、阳光、高温等季节性因素及过量锻炼、酒精摄入、化妆品使用和辛辣食物等生活习惯与疾病的严重程度密切相关.
Analysis of Lifestyle Habits and the Influencing Factors of Rosacea in 435 Patients
Objective To investigate the relationship between lifestyle habits and the onset of rosacea in 435 patients,and to identify the key factors affecting the onset of rosacea,in order to provide practical guidance for prevention and control of the disease.Methods This study used a questionnaire survey and clinical interview method,and used dermatology quality of life index(DLQI),Skindex-16,European quality of life five dimension five level questionaire(EQ-5D-5L),self-rating anxiety scale(SAS),self-rating depression scale(SDS)and Pittsburgh sleep quality index(PSQI)multi-dimensional scoring system to evaluate the basic information,clinical features,quality of life and aggravating factors of 435 rosacea patients.Statistical analysis of the collected data was used to reveal the potential connection between lifestyle habits and the onset of rosacea.Results This study predominantly analyzed 435 female patients with an average age of(40.97±11.34)years and a disease duration of(2.94±0.87)years.The main types of rosacea were erythematotelangiectatic rosacea(ETR)and papulopustular rosacea(PPR),with lesions primarily occurring on the cheeks(72.18%)and nose(64.37%).Most patients had moderate severity in erythema(66.06%)and overall condition(86.67%).DLQI,Skindex-16,SAS,and SDS indicated significant impacts on quality of life and health status.The EQ-5D-5L and VAS scores indicated that the overall health level of the patient was close to moderate,but anxiety or depression symptoms were common(49.86%).While some patients reported good sleep quality,a few faced severe sleep disturbances.Further analysis showed significant associations between rosacea severity and seasonal factors(temperature variations,sunlight,high temperatures),lifestyle habits(excessive exercise,emotional stress,alcohol consumption),menstrual cycle,cosmetic use,and spicy food intake(P<0.05).Multivariate logistic regression confirmed these factors(OR>1,P<0.05)as risk factors for rosacea severity.Conclusion Patients with rosacea experience a certain degree of decline in health-related quality of life,psychological distress,and differences in sleep quality.Seasonal factors such as temperature variations,sunlight,and high temperatures,as well as lifestyle habits including excessive exercise,alcohol consumption,cosmetic use,and spicy food intake,are closely related to the severity of the disease.

RosaceaLiving habitsPrevention strategiesQuality of life indexSleep quality index

赵婧、周舒、花卉

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南通大学附属南通第三医院,南通第三人民医院皮肤科,江苏南通 226006

玫瑰痤疮 生活习惯 预防策略 生活质量指数 睡眠质量指数

2025

中国皮肤性病学杂志
西安交通大学

中国皮肤性病学杂志

北大核心
影响因子:0.66
ISSN:1001-7089
年,卷(期):2025.39(1)