首页|甲泼尼龙治疗急性自发性荨麻疹诱发低钾性周期性麻痹2例

甲泼尼龙治疗急性自发性荨麻疹诱发低钾性周期性麻痹2例

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荨麻疹是皮肤科常见的一种免疫相关性疾病,急性荨麻疹症状严重时,常系统应用糖皮质激素治疗,常规剂量的糖皮质激素治疗荨麻疹引起的低钾性周期性麻痹临床罕见.现报告2例本科静脉应用甲泼尼龙治疗急性荨麻疹合并甲状腺功能亢进患者诱发低钾性周期性麻痹病例,提醒在临床工作中,需详细询问病史,对合并甲状腺功能亢进的患者以及其他易出现低钾性周期性麻痹风险的患者使用糖皮质激素时,要警惕出现糖皮质激素诱发低钾性周期性麻痹的可能.
Methylprednisolone in the Treatment of Acute Spontaneous Urticaria Induced Hypokalemic Periodic Paralysis:Two Cases Report
Urticaria is a common immunologically mediated disease in dermatology departments.When symptoms are severe,systemic corticosteroids are often used.It is rare to treat urticaria-associated hypokalemic periodic paralysis(HPP)with conventional doses of corticosteroids in clinical practice.Here,we report two cases in which intravenous methylprednisolone treatment for acute urticaria,combined with hyperthyroidism,induced HPP.This highlights the importance of thorough medical history inquiry in clinical practice.Clinicians should be cautious when administering corticosteroids to patients with hyperthyroidism or other conditions predisposing them to HPP,as corticosteroids may induce HPP.

MethylprednisoloneAcute spontaneous urticariaHypokalemic periodic paralysisHyperthyroidism

张培苗、尹光文、蔡丙杰、李德敬、靳利敏

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郑州大学第一附属医院皮肤科,河南郑州 450052

郑州大学第一附属医院护理部,河南郑州 450052

郑州大学第一附属医院神经内科,河南郑州 450052

甲泼尼龙 急性自发性荨麻疹 低钾性周期性麻痹 甲状腺功能亢进

2025

中国皮肤性病学杂志
西安交通大学

中国皮肤性病学杂志

北大核心
影响因子:0.66
ISSN:1001-7089
年,卷(期):2025.39(1)