A 44-year-old male presented with recurrent erythema,erosion and pruritus throughout the entire body for 3 years.Dermatological examination demonstrated diffuse erythema on the face,head,trunk and extremities,with irregular borders.Vesicles and erosions with thick brown crusts appeared on the basis of a few erythema.Enhanced abdominal CT scan revealed a mass in the body and tail of the pancreas with uneven enhancement.Laparoscopic distal pancreatectomy was performed,and glucagonoma was finally confirmed by postoperative pathologic examination.The diagnosis of necrolytic migratory erythema and glucagonoma syndrome was established.The lesions were dramatically relieved within 3 days after surgery,and the patient achieved clinical cure in 20 days,with a few pigmentation left.There have been no clinical evidence of recurrence during the 6-month follow-up period.
维普
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