Pepper is an important vegetable and ecnomic crop in China.Anthracnose seriously threatens peppers production.Breeding resistant varieties is the most basic and effevtive control measure.In this study,18 chilli pepper inbred lines were used to identify the pathogenicity of 5 different pepper anthracnose pathogens,and the strong pathogenic strains were selected to identify the aritifical inoculation resistance of 529 pepper materials.The results showed that among 402 chilii pepper inbred lines,1 showed immunity,1 showed high resistance,29 showed disease resistance,62 showed disease tolerance,and the remaining 309 materials showed susceptibility.Among 127 chilli pepper hybrid materials,3 showed immunity,1 showed high resistance,23 showed disease resistance,24 showed disease tolerance,and the remaining 76 showed susceptibility.A recombinant inbred line population was structured using parents with significant differences in pepper anthracnose resistance.The mixed major gene and polygene inheritance model of plant quantitative traits was used to conduct pepper anthracnose resistance.The results showed that the multigenic additive epistatic genetic model was the optimal model.