首页|Magnetic Resonance Imaging Studies of Neurodegenerative Disease:From Methods to Translational Research

Magnetic Resonance Imaging Studies of Neurodegenerative Disease:From Methods to Translational Research

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Neurodegenerative diseases(NDs)have become a significant threat to an aging human society.Numerous studies have been conducted in the past decades to clarify their pathologic mechanisms and search for reliable bio-markers.Magnetic resonance imaging(MRI)is a powerful tool for investigating structural and functional brain altera-tions in NDs.With the advantages of being non-invasive and non-radioactive,it has been frequently used in both animal research and large-scale clinical investigations.MRI may serve as a bridge connecting micro-and macro-level analysis and promoting bench-to-bed translational research.Nevertheless,due to the abundance and complexity of MRI techniques,exploiting their potential is not always straight-forward.This review aims to briefly introduce research pro-gress in clinical imaging studies and discuss possible strate-gies for applying MRI in translational ND research.

Magnetic resonance imagingNeurodegenerative diseaseTranslational researchAlzheimer's diseaseParkinson's disease

Peiyu Huang、Minming Zhang

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Department of Radiology,The Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China

This review was supported by the National Natural Science Foundation of ChinaThis review was supported by the National Natural Science Foundation of ChinaNatural Science Foundation of Zhejiang Province13th Fiveyear Plan for National Key Research and Development Program of China

8197157781771820LSZ19H1800012016YFC1306600

2023

10.1007/s12264-022-00905-x

神经科学通报(英文版)
中国科学院上海生命科学研究院

神经科学通报(英文版)

CSTPCDCSCD
影响因子：0.741
ISSN：1673-7067
年,卷(期)：2023.39(1)
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