首页|Immunological Markers for Central Nervous System Glia

Immunological Markers for Central Nervous System Glia

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Glial cells in the central nervous system(CNS)are composed of oligodendrocytes,astrocytes and micro-glia.They contribute more than half of the total cells of the CNS,and are essential for neural development and func-tioning.Studies on the fate specification,differentiation,and functional diversification of glial cells mainly rely on the proper use of cell-or stage-specific molecular markers.However,as cellular markers often exhibit different speci-ficity and sensitivity,careful consideration must be given prior to their application to avoid possible confusion.Here,we provide an updated overview of a list of well-established immunological markers for the labeling of central glia,and discuss the cell-type specificity and stage dependency of their expression.

Glial cellsOligodendrocytesAstrocytesMicrogliaMarkers

Hao Huang、Wanjun He、Tao Tang、Mengsheng Qiu

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Zhejiang Key Laboratory of Organ Development and Regeneration,Institute of Life Sciences,College of Life and Environmental Sciences,Hangzhou Normal University,Hangzhou 311121,China

Department of Anatomy,Cell Biology and Physiology Stark Neurosciences Research Institute,Indiana University School of Medicine,Indianapolis,IN 46202,USA

This review was supported by the National Natural Science Foundation of ChinaThis review was supported by the National Natural Science Foundation of ChinaMinistry of Science and Technology China Brain Initiative Grant

31900703321709692022ZD0204701

2023

10.1007/s12264-022-00938-2

神经科学通报(英文版)
中国科学院上海生命科学研究院

神经科学通报(英文版)

CSTPCDCSCD
影响因子：0.741
ISSN：1673-7067
年,卷(期)：2023.39(3)
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