Abstract
Glial cells in the central nervous system(CNS)are composed of oligodendrocytes,astrocytes and micro-glia.They contribute more than half of the total cells of the CNS,and are essential for neural development and func-tioning.Studies on the fate specification,differentiation,and functional diversification of glial cells mainly rely on the proper use of cell-or stage-specific molecular markers.However,as cellular markers often exhibit different speci-ficity and sensitivity,careful consideration must be given prior to their application to avoid possible confusion.Here,we provide an updated overview of a list of well-established immunological markers for the labeling of central glia,and discuss the cell-type specificity and stage dependency of their expression.
基金项目
This review was supported by the National Natural Science Foundation of China(31900703)
This review was supported by the National Natural Science Foundation of China(32170969)
Ministry of Science and Technology China Brain Initiative Grant(2022ZD0204701)
NETL
NSTL
维普
万方数据