Regulation of Glial Function by Noncoding RNA in Central Nervous System Disease

Ying Bai ¹Hui Ren ¹Liang Bian ¹You Zhou ¹Xinping Wang ¹Zhongli Xiong ¹Ziqi Liu ¹Bing Han ¹Honghong Yao²

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作者信息

1. Department of Pharmacology,Jiangsu Provincial Key Laboratory,School of Medicine,Southeast University,Nanjing 210009,China
2. Department of Pharmacology,Jiangsu Provincial Key Laboratory,School of Medicine,Southeast University,Nanjing 210009,China;Co-innovation Center of Neuroregeneration,Nantong University,Nantong 226001,China;Institute of Life Sciences,Key Laboratory of Developmental Genes and Human Disease,Southeast University,Nanjing 210009,China
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Abstract

Non-coding RNAs(ncRNAs)are a class of functional RNAs that play critical roles in different dis-eases.NcRNAs include microRNAs,long ncRNAs,and circular RNAs.They are highly expressed in the brain and are involved in the regulation of physiological and patho-physiological processes of central nervous system(CNS)diseases.Mounting evidence indicates that ncRNAs play key roles in CNS diseases.Further elucidating the mechanisms of ncRNA underlying the process of regulating glial func-tion that may lead to the identification of novel therapeutic targets for CNS diseases.

Key words

Noncoding RNA/MicroRNA/Long noncoding RNA/Circular RNA/Astrocytes/Microglia/Oligodendrocytes

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基金项目

Science and Technology innovation 2030-Major Project of the Ministry of Science and Technology of China(2021ZD0202904/2021ZD0202900)

National Science Fund Distinguished Young Scholars(82025033)

National Natural Science Foundation of China(82230115)

National Natural Science Foundation of China(82273914)

National Natural Science Foundation of China(81903591)

ZhiShan Scholar Program of Southeast University(2242022R40059)

Jiangsu Provincial Key Laboratory of Critical Care Medicine(JSKLCCM-2022-02-008)

出版年

2023

神经科学通报(英文版)

中国科学院上海生命科学研究院

神经科学通报(英文版)

CSTPCDCSCD

影响因子：0.741

ISSN：1673-7067

参考文献量131

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