Abstract
Major depressive disorder(MDD)is character-ized by emotion dysregulation.Whether implicit emotion regulation can compensate for this deficit remains unknown.In this study,we recruited 159 subjects who were healthy controls,had subclinical depression,or had MDD,and examined them under baseline,implicit,and explicit reap-praisal conditions.Explicit reappraisal led to the most nega-tive feelings and the largest parietal late positive potential(parietal LPP,an index of emotion intensity)in the MDD group compared to the other two groups;the group dif-ference was absent under the other two conditions.MDD patients showed larger regulatory effects in the LPP during implicit than explicit reappraisal,whereas healthy controls showed a reversed pattern.Furthermore,the frontal P3,an index of voluntary cognitive control,showed larger ampli-tudes in explicit reappraisal compared to baseline in the healthy and subclinical groups,but not in the MDD group,while implicit reappraisal did not increase P3 across groups.These findings suggest that implicit reappraisal is beneficial for clinical depression.
基金项目
National Natural Science Foundation of China(31970980)
National Natural Science Foundation of China(31920103009)
Major Project of National Social Science Foundation(20&ZD153)
Shenzhen-Hong Kong Institute of Brain Science(2019SHIBS0003)
Guangdong Key Project(2018B030335001)