Abstract
The increasing number of long-term survivors of pediatric brain tumors requires us to incorporate the most recent knowledge derived from cognitive neuroscience into their oncological treatment.As the lesion itself,as well as each treatment,can cause specific neural damage,the long-term neurocognitive outcomes are highly complex and chal-lenging to assess.The number of neurocognitive studies in this population grows exponentially worldwide,motivat-ing modern neuroscience to provide guidance in follow-up before,during and after treatment.In this review,we provide an overview of structural and functional brain connectomes and their role in the neuropsychological outcomes of specific brain tumor types.Based on this information,we propose a theoretical neuroscientific framework to apply appropriate neuropsychological and imaging follow-up for future clinical care and rehabilitation trials.
基金项目
Fonds voor Wetenschappelijk Onderzoek for a senior postdoctoral fellowship()
Bernard Wolfe Health Neuroscience Fund(206368/Z/17/Z)
NIHR Cambridge Biomedical Research Centre(BRC-1215-20014)
维普
万方数据