Department of Neurology,Beth Israel Deaconess Medical Center,Harvard Medical School,Boston,MA,USA

Center for Translational Pain Research,Department of Anesthesia,Critical Care and Pain Medicine,Massachusetts General Hospital,Harvard Medical School,Boston,MA,USA

Division of Pulmonary,Critical Care and Sleep Medicine,Department of Medicine,Beth Israel Deaconess Medical Center,Harvard Medical School,Boston,MA,USA

Genetics and Aging Research Unit,McCance Center for Brain Health,Mass General Institute for Neurodegenerative Disease,Department of Neurology,Massachusetts General Hospital,Harvard Medical School,Boston,MA,USA