One patient with severe follicular occlusion triad(FOT)was admitted to The First Affiliated Hospital of Guangxi University of Chinese Medicine on June 2,2022.The patient was given treatments to inhibit follicular keratinization and sebum secretion,alleviate follicular occlusion and control infection,and the local wounds at head and chest-back were managed with MEBO-impregnated gauze dressing change treatment after abscess incision and drainage,the local wound at armpit was managed with MEBO-impregnated gauze strip drainage after wound surface debridement and curettage,and the local wounds at buttocks with MEBO dressing change following radical excision,vacuum sealing drainage,and split-thickness skin grafting.All wounds were basically healed 42 days after admission.The follow-up four months after discharge found no nodules or abscess recurrence on the healed skin,and no significant discomfort was reported.