Research Progress of Optogenetic Brain-Computer Interface
As bidirectional communication systems between human brains and external devices,brain-computer interfaces(BCIs)have been widely employed in brain function enhancement,human-computer interaction and nerve rehabilitation.BCIs based on optogenetics remedy for the deficits of electrode stimulation in biological compatibility,stimulation accuracy and cell type specificity,thus becoming a hotspot in the research of neural engineering.In this review,we first described the application of optogenetic interfaces in animal experiments such as closed-loop control of brain activity,virtual sensation feedback,or brain-brain information channel.Subsequently,frontiers of novel integrated and miniaturized optogenetic interfaces were summarized.At last,we recapitulated the current challenges of optogenetic brain-computer interfaces,along with the prospects of optogenetic interface in multimodal brain activity monitoring and brain-computer intelligence.
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