Research progress in fecal microbiota transplantation in children
The normal and stable intestinal microbiota plays a key role in maintaining body health,and treatment methods based on intestinal microecology have gradually attracted attention.In recent years,fecal microbiota transplantation therapy,which restructures intestinal homeostasis in patients by transplanting intestinal microbiota in healthy people,has developed rapidly.Many studies have confirmed that fecal microbiota transplantation has a certain effect on children with clostridium difficile infection,inflammatory bowel disease,irritable bowel syndrome,constipation,nervous system diseases,allergic diseases and endocrine and metabolic diseases.This article reviews the donor selection,fecal preparation,delivery methods,and the present status and prospect of clinical application of fecal microbiota transplantation in children,in order to provide better guidance for clinical practice.