儿童肺部隐球菌感染的诊治进展
Progress in the diagnosis and treatment of pulmonary cryptococcal infection in children
殷勇 1袁姝华1
作者信息
- 1. 上海交通大学医学院附属上海儿童医学中心呼吸内科,上海 200127
- 折叠
摘要
肺部隐球菌感染是一种儿童相对罕见的肺部真菌感染性疾病,通常发生于免疫功能低下的患儿,也会在免疫正常的患儿肺部局限发生.可并发中枢神经系统隐球菌病,亦可单独发生.肺部隐球菌感染后无特异临床特征,临床诊断难度大,若不引起足够重视,极易漏诊或误诊.在免疫功能严重受损的患儿中可发生急性呼吸窘迫综合征,也可全身播散导致中枢神经系统或其他器官感染,危及生命.早期诊断及时启动抗真菌感染治疗,可以改善疾病预后.
Abstract
Pulmonary cryptococcus infection is a relatively rare pulmonary fungal infection in children.It has become an important infection in both immunocompromised and immunocompetent hosts.It is often accompanied by cryptococcosis of the central nervous system or occurs alone.Cryptococcal infection no specific clinical features,and the clinical diagnosis is difficult.If not given sufficient attention,it is highly likely to be missed or misdiagnosed.Acute respiratory distress syndrome can occur in children with severely impaired immune function,and it can also spread throughout the body,leading to central nervous system or other organ infections,which are life-threatening.Early diagnosis and timely initiation of antifungal infections can improve disease prognosis.
关键词
隐球菌/肺部/儿童Key words
cryptococcus/pulmonary/child引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据