Progress in diagnosis and treatment of pulmonary talaromyces marneffei infection in children
Talaromyces marneffei is an endemic opportunistic pathogenic fungus,mainly prevalent in Southeast Asia and southern China.Recently,the morbidity of talaromyces marneffei infection has been increasing,and most are inborn errors of immunity among children.Talaromyces marneffei mainly invades human body through the respiratory tract,which can involve multiple tissues and organs,and most commonly infects the lung.The lack of specific clinical manifestations lead to misdiagnosis or delayed diagnosis and high mortality.This article mainly introduces the talaromyces marneffei and the pathogenic mechanism,clinical characteristics,and the progress in diagnosis and treatment of its infection.
talaromyces marneffeichildpulmonarydiagn-osis and treatment