儿童肺部马尔尼菲篮状菌感染的诊治进展
Progress in diagnosis and treatment of pulmonary talaromyces marneffei infection in children
徐雪花 1卢根1
作者信息
- 1. 广州医科大学附属妇女儿童医疗中心呼吸科,广东广州 510623
- 折叠
摘要
马尔尼菲篮状菌是一种地方性机会致病真菌,主要流行于东南亚国家及中国南部.近年来,马尔尼菲篮状菌感染的发病率不断增加,在儿童中多见于免疫出生错误者.马尔尼菲篮状菌主要通过呼吸道入侵人体,感染可累及全身多组织器官,最常见的是肺部受累.儿童马尔尼菲篮状菌感染缺乏特异性的临床表现,易导致误诊或诊断延迟,病死率高.该文主要介绍马尔尼菲篮状菌及其感染的致病机制、临床特点、诊断和治疗进展.
Abstract
Talaromyces marneffei is an endemic opportunistic pathogenic fungus,mainly prevalent in Southeast Asia and southern China.Recently,the morbidity of talaromyces marneffei infection has been increasing,and most are inborn errors of immunity among children.Talaromyces marneffei mainly invades human body through the respiratory tract,which can involve multiple tissues and organs,and most commonly infects the lung.The lack of specific clinical manifestations lead to misdiagnosis or delayed diagnosis and high mortality.This article mainly introduces the talaromyces marneffei and the pathogenic mechanism,clinical characteristics,and the progress in diagnosis and treatment of its infection.
关键词
马尔尼菲篮状菌/儿童/肺部/诊治Key words
talaromyces marneffei/child/pulmonary/diagn-osis and treatment引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据