Comparison and analysis of children hospitalized for acute asthma exacarbations during COVID-19 pandemic
Objective To compare the clinical characteristics of children hospitalized for acute asthma exacerbations during the COVID-19 pandemic with those hospitalized in the previous year,and to explore the impact of the disease outbreak on disease control in children with asthma.Methods A retrospective study was conducted on 225 children hospitalized for acute asthma exacerbations at Tianjin Children's Hospital from January 1,2019 to December 31,2020.The study analyzed their general information,clinical manifestations,laboratory tests,imaging findings,and follow-up data.The patients hospitalized in 2020 were assigned to Group A,while those hospitalized in 2019 were assigned to Group B.Results Group A comprised 124 patients,and Group B comprised 101 patients.The average age at admission was 5 years in both groups,and the peak season for exacerbations was autumn in both groups.There were statistical differences between the two groups in duration of hospital stay(P=0.002),hospitalization costs(P<0.001),the rate of systemic corticosteroid use(P<0.001),the pathogen detection rate(P=0.029),and the proportion of patients with concomitant pneumonia(P=0.009).Both groups had a lower proportion of patients readmitted within one year during regular follow-up(P=0.018,P=0.045).Conclusion During the COVID-19 pandemic,a higher number of patients were hospitalized for acute asthma exacerbations,with longer duration of hospitalization,higher costs,and increased use of systemic corticosteroids.However,the pathogen detection rate decreased compared to that before the pandemic.Regular follow-up can reduce the probability of readmission for asthma in children