Research progress in the correlation between myocarditis and gene polymorphism in children
Myocarditis is an inflammatory disease of myocar-dium caused by various pathogenic factors.The clinical manifestations of myocarditis in children are complex and varied,and the severity of the disease varies.Because the onset of myocarditis is hidden,early diagnosis and timely treatment are particularly important to improve the prognosis of myocarditis.Gene polymorphism plays an important role in the occurrence and development of myocarditis in children.In this paper,we introduced the research progress on the relationship of the gene polymorphisms of Coxsackie-adenovirus receptor,human leukocyte antigen,matrix metalloproteinases,inducible nitric oxide synthase,IL-17,vitamin D receptor,monocyte chemoattractant protein-1 and non-coding RNA with myocarditis,hoping to help understand the pathogenesis of myocarditis in children better,do a good job in screening and preventing susceptible people,and provide new ideas for early diagnosis and treatment of myocarditis in children.