Research progress on surgical intervention of necrotizing enterocolitis in premature and low birth weight infants
Necrotizing enterocolitis(NEC)is a common gastrointestinal disease that occurs mostly in premature infants and low birth weight infants.It is manifested as diffuse or limited necrosis of intestinal mucosa,muscle layer or even all intestinal wall in the small intestine and colon.It is also one of the main causes of death in prematureinfants andlow birth weight infants.With the progress of medicine,especially the development of perinatal medicine and intensive care medicine,the survival rate of premature infants and low birth weight infants has been greatly increased,and the corresponding incidence of NEC in premature and low birth weight infants has also increased.If NEC cannot be controlled by conservative treatment,timely surgical intervention is required.The surgical indication and treatment timing of neonatal necrotizing enterocolitis are controversial,more so for premature and low birth weight infants.This review focuses on the clinical features,surgical indications and operation methods of premature and low birth weight infants with NEC requiring surgical intervention.