Clinical analysis of 68 cases of infantile pneumonia with bronchopulmonary dysplasia
Objective To explore the clinical characteristics of infantile pneumonia in children with different degrees and months of bronchopulmonary dysplasia.Methods Retrospective collection of medical records of 68 cases with bronchopulmonary dysplasia(BPD)who re-entered in infancy at the Third Affiliated Hospital of Zhengzhou University from January 2020 to December 2021.Results Among 68 cases(132 cases)who re-entered BPD were included.Compared with the mild BPD group,the moderate-severe BPD group had a higher proportion of neonates who received repeated use of pulmonary surfactant due to neonatal respiratory distress during the neonatal period,a longer duration of mechanical ventilation(invasive and non-invasive)and a longer total duration of oxygen therapy during hospitalization.The clinical manifestations are mainly wheezing,coughing,coarse wet rales,and wheezing,the differences are statistically significant in the comparison of different months groups(P＜0.05).Respiratory pathogens are mainly Gram-negative bacillus,and the top three special pathogens are Klebsiella pneumoniae pneumoniae,Pseudomonas aeruginosa,Staphylococcus aureus;respiratory virus detected mainly respiratory syncytial virus.The average median hospitalization time of re-entered for 13(8-21)days;60.6％of re-entered(80/132)progressed to severe pneumonia,28.8％(38/132)combined with respiratory failure.The children in the moderate/severe group had higher incidence of days,for hospitalization time and severe pneumonia,and the difference is statisically significant in the June-December months group(P＜0.05).Further logical regression analysis shows that moderate BPD(OR:2.842 95％CI:1.138～7.100)and severe BPD(OR:3.336 95％CI:1.085～10.259)are risk factors for respiratory failure.Conclusion BPD,especially moderate/severe BPD premature infants,have serious pneumonia and have been hospitalized time for a long time.It is prone to severe pneumonia and respiratory failure.Special attention should be paid to respiratory infection.
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