A case report on congenital rubella syndrome complicated with interstitial pneumonia
Congenital rubella syndrome is a disease that usually starts in infancy and is caused by rubella infection in the mother's uterus.The main manifestations are hearing impairment,congenital heart malformation,cataract/congenital glaucoma and pigmentary retinopathy,and a few may be complicated by interstitial pneumonia.Nowadays CRS is rare,and there has been no report on cases of CRS complicated with interstitial pneumonia.This article reports a case of URS complicated with interstitial pneumonia starting in infancy who were hospitalized in the Guangzhou women and Children's Medical Center from November 29,2020.The main clinical manifestations were interstitial pneumonia,cataract,hearing impairment,congenital heart malformation,etc.Serum rubella virus-IgM was positive,the alveolar lavage fluid was detected by high throughput seguencing and rubella virus was found,and chest CT showed uniform ground glass interstitial changes in both lungs,which confirmed the diagnosis of CRS complicated with interstitial pneumonia.This article aims to study the harm and prognosis of the disease and strengthen the attention of clinicians by analyzing the pathogenesis,clinical manifestations,laboratory indicators,imaging manifestations,treatment and prognosis of CRS complicated with interstitial pneumonia.