Association between adenotonsillectomy and allergic rhinitis in children:A longitudinal database analysis
Objective This study aimed to explore the impact of obstructive sleep apnea(OSA)on Allergic rhinitis(AR)in children by analyzing the changes in AR treatment after adenotonsillectomy(AT).Methods The patients with AR who underwent AT from 2015 to 2018 were recruited as surgical group.According to the time of outpatient and emergency visits,age and gender,propensity score matching(PSM)was used to match the children at 1∶2 as the control group.The number of visits,medical costs and medication prescriptions were compared respectively between the two groups one year before and one year after surgery.Primary outcomes included number of visits,total cost of visits,total cost of medications,total cost of AR medicationsand itschange.Results This study included 205 patients in the surgical group(AT)and 508 patients in the control group.There was no statistically significant difference in the number of visits between the surgical group and the control group in the first year/pre-operation(P=0.22).The total cost,cost of medications,cost of AR medications of surgical group were higher than those of the control group(P<0.001,0.001,and 0.002,respectively).The number of visits in the surgical group decreased by 28.3%one year after AT(95%CI:25.2%~31.7%,P<0.001).The total medical expenses,total drug expenses,and AR drug expenses of the surgical group decreased one year after AT:total medical expenses(37.5%,95%CI:37.3%~37.6%,P<0.001),total drug expenses(39.1%,95%CI:38.8%~39.3%,P<0.001),and AR drug expenses(39.5%,95%CI:39.1%~39.8%,P<0.001).Conclusion AT can reduce the number of hospital visits and the cost of treatment and medication.Monitoring and treating adenoid and tonsil hypertrophy and OSA may help to optimizetreatment strategies for AR control.