双胎妊娠非整倍体异常的产前筛查与产前诊断
Prenatal screening and prenatal diagnosis of aneuploidy in twin pregnancy
刘俊涛 1周希亚1
作者信息
- 1. 中国医学科学院北京协和医学院北京协和医院妇产科,北京100730
- 折叠
摘要
双胎妊娠非整倍体产前筛查较单胎复杂.应在早孕期确定孕周、绒毛膜性并测量颈项透明层厚度.早孕期联合筛查优于中孕期血清学筛查,但检出率明显低于单胎妊娠.无创产前检查用于双胎筛查仍需更多研究数据.双胎之一胚胎停育将影响早孕期筛查的准确性.产前诊断时区分标记双胎是需要注意的重要问题.
Abstract
Prenatal aneuploidy screening is more complicated in twin pregnancy than in singleton pregnancy.Gestational age,chorionicity and NT should be determined at first trimester.Combined screening test at first trimester is better than second trimester screening,but the detection rate is lower than that of singleton pregnancy.NIPT in twins is still under research.Vanishing twins will surely affect the accuracy of prenatal screening.It is important to distinguish each twin when doing prenatal diagnosis.
关键词
双胎妊娠/产前筛查/产前诊断/无创产前检测/双胎之一胚胎停育Key words
twin pregnancy/prenatal screening/prenatal diagnosis/non-invasive prenatal test/vanishing twins引用本文复制引用
出版年
2015
国家科技期刊平台
NSTL
维普
万方数据