Primary clear cell adenocarcinoma of the uterine cervix:a clinicopathological analysis of 32 patients
Objective To investigate the clinical and pathological features and prognosis of primary clear cell adenocarcinoma of the uterine cervix(PCCAC).Methods Thirty-two patients diagnosed with PCCAC and treated at Qilu Hospital of Shandong University from January 2013 to January 2023 were collected,their clinical and pathological characteristics were analyzed,and the Log-rank test was performed to explore factors associated with patient survival.Results The median age of the thirty-two patients was 48 years.All patients underwent hysterectomy and pelvic lymphadenectomy,and the unilateral or bilateral ovaries were preserved in 5 cases.The median follow-up was 45 months(ranging,1-116 months),1 case was lost to followup,3 patients died of multiple organ dysfunction syndrome due to recurrence and metastasis,and 1 patient recurred but the prognosis was good after comprehensive treatment;no recurrence or metastasis was found in the follow-up of the remaining patients.Log-rank test showed that age＞50 years,menopause,endogenous or cervical canal type and corpus uteri invasion were associated with worse prognosis(P＜0.05).Conclusion Age＞50 years,menopause,endogenous or cervical canal type and corpus uteri invasion may be prognostic factors for survival of PCCAC patients.Ovarian preservation does not seem to affect the prognosis of patients.
clear cell adenocarcinoma of the uterine cervixprognosisovarian metastasisovarian-preserving
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