子宫颈缝合成形术与Sturmdorf缝合法在高级别鳞状上皮内病变子宫颈锥切术中应用效果比较研究
Analysis of the application of modified cervical suture plasty and Sturmdorf suture in the operation of high-grade squamous intraepithelial lesions
何剑颖 1沈婷 1寿坚1
作者信息
- 1. 杭州师范大学附属萧山医院,浙江杭州 311200
- 折叠
摘要
目的 探讨子宫颈缝合成形术与Sturmdorf缝合法在高级别鳞状上皮内病变(high-grade squamous intraepi-thelial lesion,HSIL)子宫颈锥切术中应用的效果.方法 选取2021年1月至2023年1月在杭州师范大学附属萧山医院行子宫颈锥切术治疗的87例HSIL患者作为研究对象,根据缝合方式不同分为子宫颈缝合成形术组(研究组,44例)和Sturmdorf缝合法组(对照组,43例),收集两组患者围手术期各项资料,比较两组患者术中及术后24 h出血量、术后应激反应指标(去甲肾上腺素、醛固酮、血管紧张素Ⅱ)的表达、术后3个月子宫颈塑形满意度及并发症发生情况.结果 (1)研究组患者术中及术后24h出血量与对照组患者相比更低[分别为(18.68±5.26)mL vs.(13.54±4.73)mL 和(21.57±4.68)mL vs.(10.35±4.65)mL,均P＜0.001].(2)研究组患者术后去甲肾上腺素、醛固酮、血管紧张素 Ⅱ 表达较对照组患者更低[分别为:(121.73±10.68)μg/Lvs.(100.21±10.57)μg/L、(121.41±15.47)μg/L vs.(84.72±10.69)μg/L、(54.21±7.51)μg/Lvs.(31.54±5.97)μg/L,均P＜0.001].(3)研究组患者术后3个月子宫颈塑形满意度较对照组患者更高(88.64％vs.74.42％,P＜0.05).(4)研究组患者并发症总发生率与对照组患者相比更低(6.82％vs.18.60％,P＜0.05).结论 对行子宫颈锥切术治疗的HSIL患者使用子宫颈缝合成形术缝合能显著减少出血量,降低应激反应对机体造成的不必要损伤,子宫颈塑形良好,可作为HSIL患者手术缝合的首选方法.
Abstract
Objective Objective To compare the efficacy of modified cervical suture plasty versus Sturmdorf suture on stress response and cervical shaping in patients with highly squamous intraepithelial lesions(high-grade squamous in-traepithelial lesion,HSIL).Methods A total of 87 patients with HSIL who underwent cervical conization in Xiaoshan Hospital Affiliated to Hangzhou Normal University from January 2021 to January 2023 were selected as the study sub-jects,and were divided into modified cervical suture plasty group(study group,44 cases)and Sturmdorf suture group(control group,43 cases)according to different suture methods.Collecting the perioperative data of two groups,and com-paring the intraoperative and 24-hour postoperative blood loss,the expression of postoperative stress response indexes(norepinephrine,aldosterone,angiotensin Ⅱ),satisfaction with cervical shaping and the occurrence of complications at 3 months after surgery between the two groups.Results(1)The intraoperative and 24-hour blood loss in the study group was lower than that in the control group[(18.68±5.26)mL vs.(13.54±4.73)mL and(21.57±4.68)mL vs.(10.35±4.65)mL,both P＜0.001)].(2)The expression of norepinephrine,aldosterone,and angiotensin Ⅱ in the study group was lower than that in the control group[(121.73±10.68)μg/L vs.(100.21±10.57)μg/L,(121.41±15.47)μg/L vs.(84.72±10.69)μg/L,(54.21±7.51)μg/L vs.(31.54±5.97)μg/L,P＜0.001].(3)Compared with the control group,the satisfaction of the patients in the study group was higher than that in the control group at 3 months af-ter surgery(88.64％vs.74.42％,P＜0.05).(4)The total incidence of complications in the study group was lower than that in the control group(6.82％vs.18.60％,P＜0.05).Conclusion The use of modified cervical suture plasty in HSIL patients treated with cervical conization can sig-nificantly reduce the amount of bleeding,reduce unnec-essary damage to the body caused by stress response,and have good cervical conformation,which can be used as the preferred method of surgical suturing in HSIL patients.
关键词
子宫颈缝合成形术/子宫颈锥切术/出血量/子宫颈塑形Key words
modified cervical suture plasty/cervical conectomy/blood volume/cervical shaping引用本文复制引用
基金项目
浙江省医药卫生科技计划项目(2023KY1013)
出版年
2024
国家科技期刊平台
NSTL
万方数据