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妊娠合并灾难性抗磷脂综合征

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灾难性抗磷脂综合征罕见,多数病例在1周内可发生全身广泛性血栓形成,导致严重的多器官功能障碍,死亡率极高.妊娠是灾难性抗磷脂综合征的高危因素,伴随着妊娠、分娩相关手术、感染、凝血功能和免疫功能改变更是增加了妊娠女性发生灾难性抗磷脂综合征的风险.早期识别疑似患者,予以血浆置换等积极治疗手段,是改善预后的重要举措.
Pregnancy complicated with catastrophic an-tiphospholipid syndrome
Catastrophic antiphospholipid syndrome(CAPS)is a rare disease,and most cases suffer from severe extensive thrombosis,resulting in multiple organ failure,so mortality is very high.Pregnancy is an independent risk factor for CAPS,and surgery,in-fection,and changes in coagulation and immunology due to pregnancy and delivery increase the risk for CAPS in pregnant women.Early identification of the suspected patients and active treatment of plasma ex-change are important measures to improve the prog-nosis.

catastrophic antiphospholipid syn-dromeantiphospholipid antibodythrombotic micro-angiopathy

刘亚敏、周玮

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重庆医科大学附属妇女儿童医院/重庆市妇幼保健院妇产科,重庆 401147

灾难性抗磷脂综合征 抗磷脂抗体 血栓性微血管疾病

2024

中国实用妇科与产科杂志
中国医师协会 中国实用医学杂志社

中国实用妇科与产科杂志

CSTPCD北大核心
影响因子:1.97
ISSN:1005-2216
年,卷(期):2024.40(12)