聚乙二醇电解质散全胃肠道灌洗联合常规导泄治疗敌草快中毒的应用效果
Application of Polyethylene Glycol Electrolyte Powder Whole Gastrointestinal Lavage Combined with Conventional Catheterization in the Treatment of Diquat Poisoning
刘旭 1陈晓婷1
作者信息
- 1. 510620 广东 广州,广州市第十二人民医院
- 折叠
摘要
目的 分析聚乙二醇电解质散全胃肠道灌洗联合常规导泄治疗敌草快中毒的应用效果.方法 选择2019年8月—2023年8月广州市第十二人民医院收治的82例敌草快中毒患者,随机分为常规组和联合组各41例.常规组进行常规导泄救治;联合组在常规组基础上,加用聚乙二醇电解质散全胃肠道灌洗,比较两组患者的治疗结局.结果 联合组总有效率高于常规组,差异有统计学意义(P＜0.05).联合组多器官功能障碍综合征、肺纤维化发生率及病死率低于常规组,差异有统计学意义(P＜0.05).治疗3 d后,两组生化指标、炎症因子指标较治疗前均降低,且联合组低于常规组,差异有统计学意义(P＜0.05).结论 聚乙二醇电解质散全胃肠道灌洗联合常规导泄治疗敌草快中毒效果显著,能降低多器官功能障碍综合征、肺纤维化发生率及病死率,并且降低生化指标和炎症因子水平.
Abstract
Objective To analyze the application effect of polyethylene glycol electrolyte powder whole gastrointestinal lavage combined with conventional catheterization in the treatment of diquat poisoning.Methods A total of 82 patients treated in the Twelfth People's Hospital of Guangzhou from August 2019 to August 2023 were randomly divided into conventional group and combined group,with 41 cases in each group.The conventional group was treated with conventional drainage treatment,and the combined group was treated with polyethylene glycol electrolyte powder based on conventional group.The treatment outcomes of the two groups were compared between the two groups.Results The total effective rate of combined group was significantly higher than that of conventional group(P<0.05).The incidence of multiple organ dysfunction syndrome,pulmonary fibrosis and mortality in combined group were significantly lower than those in conventional group(P<0.05).After 3 days of treatment,the levels of biochemical indexes and inflammatory factors in both groups were significantly decreased compared with before intervention,and the combined group was significantly lower than the conventional group(P<0.05).Conclusion The application of polyethylene glycol electrolyte powder combined with conventional drainage in the treatment of diquat poisoning patients could significantly reduce the incidence of multiple organ dysfunction syndrome,pulmonary fibrosis,and mortality,and it could also reduce the levels of biochemical indicators and inflammatory factors.
关键词
聚乙二醇电解质散/胃肠道灌洗/导泄/敌草快/中毒Key words
Polyethylene Glycol Electrolyte Powder/Gastrointestinal Lavage/Induce Leakage/Diquat/Poisoning引用本文复制引用
出版年
2024
NETL
NSTL
万方数据