AIM: To study the chemical constituents of the whole plant of Solanum lyratum. METHODS: The compounds were isolated by column chromatography over silica gel and RP-C15, and purified by Sephadex LH-20 and preparative TLC. Their structures were elucidated on the basis of physicochemical property and spectral data. RESULTS: Eleven compounds were isolated and identified as: diosgenin (1), tigogenin (2), syringaldehyde (3), sy-ringic acid (4), 4-hydroxybenzaldehyde (5), scopoletin (6), N-cis-feruloyltyramine (7), β-sitosterol (8), daucosterol (9), erythritol (10) and mannitul (11). CONCLUSION: Compound 7 has been separated from Solanaceae plant for the first time, compounds 10 and 11 have been isolated from Solanum plant for the first time, and compounds 3-5 have been ob-tained from this plant for the first time.
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