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华东唐松草的化学成分

Chemical Constituents from Thalictrum fortunei

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目的:对华东唐松草(Thalictrum fortunei)化学成分进行分离并鉴别化学结构.方法:利用各种柱色谱方法对其乙醇提取物的正丁醇部位进行分析,用UV、IR、MS、1H NMR、13C NMR等光谱技术鉴定化合物结构.结果:分离鉴定了11个化合物,分别为O-甲基唐松草檗碱(O-methylthalicberine)(1),24S-lanost-9(11)-erie-3β,16β,24,25,30-pentaol(2),胆固醇(cholester01)(3),β-谷甾醇(β-sitoster01)(4),豆甾醇(stigmasterol)(5),豆甾醇3-O-β-D-吡喃葡萄糖苷(stigmasterol 3-O-β-D-glucopyranoside)(6),菠菜甾醇3-O-β-D-吡喃葡萄糖苷(spinasteml 3-O-β-O-glucopyranoside)(7),胡萝卜苷(daucoster01)(8),蔗糖(sucrose)(9),邻二苯甲酸正丁酯(palatinol C)(10),对羟基正丁基酚醚(4-butyloxyphen01)(11).结论:化合物1-11均为首次从该植物中分离得到.
AIM: To study the chemical constituents from the aerial parts of Thalictrumfortunei. METHODS: Various column chromatographic methods were carried out for the isolation and purification of the compounds from the EtOH extract of T. fortunei. Their structures were elucidated by the combined analysis of UV, IR, MS, 1H and 13C NMR spectral data. RUSULTS: Eleven compounds were obtained, and their structures were elucidated as O-methylthalicberine (1), 24S-lanost-9(11)-ene-3β, 16β, 24, 25, 30-pentaol (2), cholesterol (3), β-sitosterol (4), stigmas-terol (5), stigmasterol 3-O-β-D-glucopyranoside (6), spinasterol 3-O-β-D-glucopyranoside (7), daucostero (8), sucrose (9), palatinol C (10) and 4-butyloxyphenol (11), respectively. CONCLUSION: All compounds were isolated from this plant for the first time.

Thalictrum fortunei S. MooreRanunculaceaeChemical constituents

张现涛、张雷红、王英、李艳、王玉生、叶文才

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广东省中药研究所,广州,510520

暨南大学中药及天然药物研究所,广州,510632

中国药科大学中药学院,南京,210038

华东唐松草 毛莨科 化学成分

2009

10.3724/SP.J.1009.2009.00293

中国天然药物
中国药科大学,中国药学会

中国天然药物

CSTPCD北大核心
影响因子：0.859
ISSN：1672-3651
年,卷(期)：2009.7(4)
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