光叶海桐根的化学成分
Chemical Constituents of Pittosporum glabratum
聂田田 1赵焕新 1白虹1
作者信息
- 1. 山东省医学科学院药物研究所,山东省罕少见病重点实验室,济南,250062
- 折叠
摘要
目的:对光叶海桐根的化学成分进行研究.方法:通过多种柱层析方法和制备高效液相对化合物进行分离纯化.通过理化常数及波谱数据对其结构进行解析.结果:从光叶海桐根中分离得到7个化合物,分别鉴定是6α-羟基.京尼平苷(1).10-O-咖啡酰基-脱乙酰基-交让木苷(2),(+)-南烛木树脂酚-3α-D-β-D-葡萄糖苷(3),(+)-南烛木树脂酚-3α-D-(6"-3,5-二甲氧基-4-羟基-苯甲酰基)-β-D-葡萄糖苷(4),(+)-南烛木树脂酚-3α-O-(6"-3-甲氧基-4-羟基-苯甲酰基)-β-D-葡萄糖苷(5),(-)-4-epi-南烛木树脂酚-3α-D-β-D-葡萄糖苷(6)和(+)-丁香脂素-4,4'-O-双-β-D-葡萄糖苷(7).结论:化合物1-6为该属首次分离,化合物7为该种首次分离.
Abstract
AIM: To investigate the chemical constituents of Pittosporum glabratum LindL METHODS: The compounds were isolated and purified by repeated column chromatography and preparative HPLC. The structures were elucidated on the basis of spec-troscopic analyses and physical evidence. RESULTS: Seven compounds were isolated and identified as 6α-hydroxygeniposide (1), 10-O-caffeoyl deacetyl daphylloside (2), (+)-lyoniresmol-3α-O-β-D-glucopyranoside (3), (+)-lyoniresinol-3α-O-(6"-3,5-dimethoxy-4-hydroxybenzoyl)-β-D-glucopyranoside (4), fernandoside [(+)-lyoniresinol-3α-O-(6"-3-methoxy-4-hydroxybenzoyl)-β-D-glucopy-ranoside] (5), (-)-4-epi-lyoniresinol-3α-O-β-D-glucopyranoside (6) and liriodendrin [(+)-syringaresinol-4,4'-bis-O-β-D-glucopy-ranoside] (7). CONCLUSION: Compounds 1-6 were found in the genus Pittosporum for the first time and 7 was isolated from the plant Pittosporum glabratum for the fust time.
关键词
光叶海桐根/化学成分/环烯醚萜苷/木脂素苷Key words
Pittosporum glabratum/Chemical constituent/Iridoid glycoside/Lignan glycoside引用本文复制引用
出版年
2011
NETL
NSTL
维普
万方数据