Research Progress of Synthesis of Hemoglobin by Microorganisms and Its Application in Food
Hemoglobin is a heme protein composed of heme subunits and globin peptide chains that exists in prokaryotic and eukaryotic cells.It has various physiological functions and is often used in the pharmaceutical and food industries.In the field of food processing,it can be used as a seasoning agent to improve the taste and authenticity of future meat substitutes-plant protein meat,so as to meet the needs of people with special nutritional requirements for meat taste.Using microbial fermentation method to produce hemoglobin has advantages compared with chemical method,it is easy to operate,economical,efficient and environmentally friendly,and has become a research hotspot in recent years.The key to efficient expression of hemoglobin by microorganisms lies in two aspects:the high-level supply of hemoglobin and the correct expression of hemoglobin.Strengthening the heme synthesis pathway,optimizing protein expression and fermentation strategies are important ways to achieve efficient expression of hemoglobin.In this paper,the latest research progress of the efficient synthesis of hemoglobin by microorganisms,as well as the application of hemoglobin and its derivatives in food are reviewed,in order to provide theoretical references for promoting the application of microbial derived hemoglobin in food.
hemoglobinhemevegetable protein meatfuture foodfood seasoning