Research Progress of Rotating Drum Solid-State Bioreactors
Solid-state fermentation refers to the growth and metabolism of microorganisms on solid materials with extremely low water content to obtain the primary and secondary metabolites.Solid-state reactors are increasingly widely used in the fields such as food fermentation,biopharmaceuticals and feed production due to their online monitoring and automatic control of various process parameters.Different control modes are adopted according to the process parameters such as tank temperature,dissolved oxygen and pH.In the solid-state fermentation process,due to the differences in the growth environment of microorganisms,materials,mass transfer and many other factors,designing reactors and achieving intelligence and programming are the key common issues that need to be solved.In this paper,the application and characteristics of rotating drum solid-state bioreactors are mainly analyzed,and the questions about some drawbacks at present are raised.
万方数据
维普
