The Regulation and Molecular Mechanism of Exercise on Gut Microbiota Homeostasis in Microgravity Environment
Microgravity environment can reduce the diversity of the gut microbiota,decrease the levels of probiotics,cause the dysfunction of gut microbiota,and promote the production of harmful metabolites in the body,which can damage multiple organs and negatively impact the physical and mental health of astronauts.Exercise can improve the physical and mental health of astronauts to some extent,but the mechanism of improving gut microbiota disorders in micro-gravity environment is still unclear.Literature review method was used to explore the effects of microgravity environment and exercise on the gut microbiota,and the molecular mechanisms by which exercise improves gut microbiota homeostasis in microgravity environment.It has been found that exercise in the microgravity environment effectively promotes the physical and mental health of astronauts by increasing the diversity of the gut microbiota,regulating the im-mune response of the intestinal mucosa,enhancing the function of the intestinal barrier,activat-ing metabolism-related signaling pathways,and the gut-microbiota-brain axis.
万方数据
维普
