首页|Small-angle X-ray scattering probe of intermolecular interaction in red blood cells

Small-angle X-ray scattering probe of intermolecular interaction in red blood cells

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With high concentrations of hemoglobin (Hb) in red blood cells,self-interactions among these molecules could increase the propensities of their polymerization and aggregation.In the present work,high concentration Hb in solution and red blood cells were analyzed by small-angle X-ray scattering.Calculation of the effective structure factor indicates that the interaction of Hb molecules is the same when they are crowded together in both the cell and physiological saline.The Hb molecules stay individual without the formation of aggregates and clusters in cells.

small-angle X-ray scatteringprotein-protein interactionhemoglobin

LIU Guan-Fen、WANG We-Jia、XU Jia-Hua、DONG Yu-Hui

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Beijing Synchrotron Radiation Facility, Institute of High Energy Physics,Chinese Academy of Sciences, Beijing 100049, China

National Basic Research Program of ChinaNational Natural Science Foundation of China

2009CB91860010979005

2015

中国物理C(英文版)
中国物理学会 中国科学院高能物理研究所 中国科学院近代物理研究所

中国物理C(英文版)

CSTPCDCSCDSCI
影响因子:0.347
ISSN:1674-1137
年,卷(期):2015.39(3)
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