中国物理B(英文版)2024,Vol.33Issue(7) :645-650.DOI:10.1088/1674-1056/ad3dcc

Model-driven CT reconstruction algorithm for nano-resolution x-ray phase contrast imaging

谭雨航 蔡学宝 杨杰成 苏婷 郑海荣 梁栋 朱佩平 葛永帅
中国物理B(英文版)2024,Vol.33Issue(7) :645-650.DOI:10.1088/1674-1056/ad3dcc

Model-driven CT reconstruction algorithm for nano-resolution x-ray phase contrast imaging

谭雨航 1蔡学宝 2杨杰成 1苏婷 1郑海荣 3梁栋 3朱佩平 4葛永帅3
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作者信息

  • 1. Research Center for Medical Artificial Intelligence,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,China
  • 2. Institute of Electronic Paper Displays,South China Academy of Advanced Optoelectronics,South China Normal University,Guangzhou 510006,China
  • 3. Research Center for Medical Artificial Intelligence,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,China;Paul C Lauterbur Research Center for Biomedical Imaging,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,China
  • 4. Institute of High Energy Physics,Chinese Academy of Sciences,Beijing 100049,China
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Abstract

The low-density imaging performance of a zone plate-based nano-resolution hard x-ray computed tomography(CT)system can be significantly improved by incorporating a grating-based Lau interferometer.Due to the diffraction,however,the acquired nano-resolution phase signal may suffer splitting problem,which impedes the direct reconstruction of phase contrast CT(nPCT)images.To overcome,a new model-driven nPCT image reconstruction algorithm is developed in this study.In it,the diffraction procedure is mathematically modeled into a matrix B,from which the projections without signal splitting can be generated invertedly.Furthermore,a penalized weighted least-square model with total variation(PWLS-TV)is employed to denoise these projections,from which nPCT images with high accuracy are directly reconstructed.Numerical experiments demonstrate that this new algorithm is able to work with phase projections having any splitting distances.Moreover,results also reveal that nPCT images of higher signal-to-noise-ratio(SNR)could be reconstructed from projections having larger splitting distances.In summary,a novel model-driven nPCT image reconstruction algorithm with high accuracy and robustness is verified for the Lau interferometer-based hard x-ray nano-resolution phase contrast imaging.

Key words

splitting phase image/reconstruction algorithm/grating interferometer

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基金项目

National Natural Science Foundation of China(12027812)

Guangdong Basic and Applied Basic Research Foundation of Guangdong Province,China(2021A1515111031)

出版年

2024
中国物理B(英文版)
中国物理学会和中国科学院物理研究所

中国物理B(英文版)

CSTPCDEI
影响因子:0.995
ISSN:1674-1056
参考文献量14
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