Effect of Continuous Renal Replacement Therapy Combined With Percutaneous Coronary Intervention in the Treatment of Severe Acute Myocardial Infarction Combined Acute Renal Insufficiency
Objective To investigate the effects of continuous renal replacement therapy(CRRT)combined with percutaneous coronary intervention(PCI)on vital signs,liver and kidney function,complication in patients with severe acute myocardial infarction(SAMI)combined acute renal insufficiency.Methods Sixty SAMI combined acute renal insufficiency patients in Fujian Provincial Hospital from March 2021 to April 2023 were selected as the research objects and divided into control group and observation group using a random number table method,with 30 patients in each group.The control group received simple PCI treatment,the observation group received CRRT treatment based on the control group.The vital signs,liver and kidney function indicators and complications of the two groups were compared.Results After treatment,systolic blood pressure(SBP),diastolic blood pressure(DBP),and heart rate(HR)in the observation group were(112.35±15.39)mmHg,(74.25±9.37)mmHg and(69.73±3.87)beats/min,respectively,which were lower than(121.82±19.28)mmHg,(81.36±11.02)mmHg,and(74.11±5.02)beats/min in the control group(P=0.039,P=0.009,P<0.001).After treatment,the total bilirubin(TBIL),aspartate transaminase(AST),blood urea nitrogen(BUN)and creatinine(Cre)in the observation group were(18.07±2.98)μmol/L,(35.87±5.23)U/L,(11.47±1.87)mmol/L,(79.48±7.25)μmol/L,which were lower than(21.32±3.14)μmol/L,(46.12±8.91)U/L,(13.08±2.08)mmol/L,(87.23±10.36)μmol/L in the control group(P<0.001,P<0.001,P=0.002,P=0.001).The incidence of complications in the observation group(3.33%)was lower than that in the control group(26.67%)(P=0.030).Conclusion The combination of CRRT and PCI can more effectively stabilize the vital signs of SAMI combined acute renal insufficiency patients,improve their liver and kidney function,and reduce the occurrence of complications.